PCT (Post Cycle Therapy)
Post Cycle Therapy is a set of drugs taken to restore the normal functioning of the body after the course of AAS (androgenic-anabolic steroids). First of all, the endocrine system. This is necessary for:
- Control of side effects on the course;
- Restoration of the natural level of hormones;
- Minimizing the loss of muscle mass after the course;
- Avoidance of side effects from AAS. Such as testicular atrophy or gynecomastia.
On the course (without changing the set and dosages of the steroids taken), it is possible to control their aromatization and progestogenic activity. It is also possible to maintain the function of the testicles to produce testosterone. All this is done by taking additional medications.
Aromatization, that is, the conversion of androgens to estrogens, can be controlled in two ways. You can block the action of estrogen on the receptors, and you can prevent the process of aromatization (aromatase inhibitors). Accordingly, there are two different classes of drugs with a different mode of action.
Estrogen receptor blockers
These drugs act by joining estrogen receptors and thereby blocking estrogen access to them. This group includes clomid (clomiphene), toremifene, tamoxifen.
In Russia, tamoxifen is available in pharmacies, and at the same time it is the most effective and cheap. In this case, tamoxifen has a number of very useful side effects. The main of them is a direct increase in the synthesis of luteinizing hormone (LH). The function of LH is the stimulation of the testicles. That is an increase in the production of testosterone and spermatozoa. Tamoxifen is so effective that after 10 days of its intake of 20 mg per day, the production of testosterone increases by 42% compared with the baseline. And after 6 weeks of admission – by 83%.
Also under the influence of tamoxifen, there is an increase in the production of high-density lipoproteins, which is the prevention of the development of atherosclerosis.
However, with all the advantages of tamoxifen, it is not recommended to take it to suppress aromatization during the administration of AAS, as this greatly reduces the effectiveness of taking steroids. Basically, it is used immediately after the abolition of steroid preparations.
Categorically, estrogen receptor blockers should not be used simultaneously with taking steroids with progestagenic activity – nandrolone, trenbolone, oximetalone. This will greatly enhance their side effects.
On the AAS course, tamoxifen is acceptable if you use only drugs that are not prone to aromatization and progestagenic activity (boldenone, statazolol, turinabol, oxandrolone, primobolan, etc.). In this case tamoxifen will be useful for the least influence of AAS on the secretion of endogenous testosterone and leveling the properties of steroids to reduce the production of high-density lipoproteins.
Effective dosages of tamoxifen – 20-60 mg / day, it is recommended to divide the dose into 2-3 doses. Determine what kind of dosage is needed for you after the AAS course, a simple rule will help.
- The total dose of AAS is less than 500 mg / week – 20 mg / day of tamoxifen.
- 500-1000 mg / week – 40 mg / day.
- More than 1000 mg / week – 60 mg / day.
Take tamoxifen should be at least 3-4 weeks after the course, and preferably longer. Up to the beginning of the next course.
Aromatase inhibitors are the second class of drugs to control the work of estrogens in the body. These are drugs such as proviron, letrozole and anastrazole. It is advisable to use them both during and after the course. Nevertheless, they also reduce the effect of the course.
Proviron is not only an aromatase inhibitor, but also increases libido and increases the amount of sperm produced. That is extremely useful for the restoration of the testicles. Dosages of 25-75 mg / day are used.
Letrozole and anastrazole are very similar to each other. To prevent side effects on the course, a dosage of 0.5 mg every other day is used. For the treatment of gynecomastia – 1 mg / day for anastrazole and 2.5 mg / day for letrozole. Both of these drugs have a beneficial effect on the secretion of testosterone, but at high dosage lower libido.
Control of progestogen activity
To control progestagenic activity of steroids, two drugs are used: bromocriptine and dostinex (cabergoline). However, the use of bromocriptine is a thing of the past. This is due to the fact that Dostinex significantly exceeds it in all parameters. A bromocriptine has a number of unpleasant side effects, such as nausea and loss of appetite.
Dostinex very effectively inhibits the production of prolactin and the transformation of AAS into progesterone. And as a consequence, increases the secretion of prolactin. Let me remind you that this property (transformation into progesterone) is inherent only in three drugs – trenbolone, nandrolone and oxymetalone. Suppression of progestagenic activity increases libido, lowers blood pressure, reduces the decrease in testosterone production. Also, the effect of taking AAS is reduced.
Dosage of dostinex is 0.25 mg (1/4 tablet) every four days. Even this scanty amount is enough to suppress side effects even from high dosages of AAS.
Increased testosterone production
In addition to using drugs that suppress female sex hormones, chorionic gonadotropin is used to increase the production of testosterone. In its essence, gonadotropin is an analog of the luteinizing hormone (LH), but it is not produced by the pituitary gland, but by the yellow body in the placenta of pregnant women, from whose urine this drug is isolated.
Thus, gonadotropin, like LH, stimulates the secretion of hormones in the testicles, therefore it has the same effects as testosterone. Accordingly, spermatogenesis increases, the testes restore their size after the AAS course.
Chorionic gonadotropin should be used only while you are still on the course, as it suppresses your own production of LH, which is absolutely unacceptable during the restoration of the entire hormonal system as a whole.
The most productive scheme with minimal suppression of LH production is the subcutaneous injection of 500-1000 ED of gonadotropin every three days. In general, the course of gonadotropin, as a rule, is enough 5-10 thousand units of the drug.
Restoration of the hormonal system and preservation of muscle mass
1. Testosterone boosters – such as ecdysterone (at a dosage of 100-300 mg / day) and D-aspartic acid (3-4 grams per day). They will help the body to restore the secretion of testosterone and, in general, feel better.
2. Growth Hormone – has anti-catabolic activity. Dosage – 10 units per day, it is recommended to divide the daily dose by 2-3 doses. It also enhances the effect of AAS, burns fat, restores joints and ligaments.
3. Sports nutrition – especially protein supplements and BCAA (3-5 times a day for 10 gr.). Have anti-catabolic effect.
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